Modafinil is a substance that has been used in the treatment of narcolepsy for years. However, modafinil has become more widely known only recently, when corporate employees, students and athletes started using it on a large scale. It is said that even US President Barack Obama received him. Modafinil - like other psychostimulants, e.g. amphetamine - increases physical and mental performance, but unlike them, it does not have side effects and is not addictive. Are you sure?
Modafinil (also known as the smart drug) is a stimulant and is found in some medications. Modafinil is currently approved in dozens of European countries, but the indications for its use vary between Member States. In all the countries of the community, the indication is narcolepsy - a disease involving sudden falling into a short sleep, regardless of the situation in which the patient is. In addition, in some European Union countries the indications for its use are idiopathic hypersomnia (excessive sleepiness), obstructive sleep apnea (OSA), and chronic sleep disorders associated with moderate to severe shift work. In some countries, it is also used off-label - e.g. to improve concentration in people with ADHD. In Poland, modafinil was available in the form of a drug called Vigil, but a few years ago it was withdrawn from the market. Currently, in our country, other stimulants, e.g. methylphenidate, are used in patients suffering from narcolepsy. Those patients with contraindications to the use of methylphenidate receive modafinil as part of target import with an individual refund. There is also another way to buy it - on the black market. This path is chosen by corporate employees, students, athletes and others who do not have time to sleep and need psychomotor stimulation.
Modafinil - action. Modafinil effects
The trade names of modafinil vary by country. It is known as Provigil in the US, UK, Hong Kong and several other countries. In Japan and France it is sold as Modiodal, and in Switzerland it is sold as Modasomil.
It quickly turned out that white tablets containing modafinil can free not only sick people but also healthy people from sleep. Supposedly, thanks to modafnil, you can stay awake for nearly 64 hours (although some sources say even 70 hours) without fatigue, loss of mental performance or reflexes. And you do not need to sleep afterwards - the use of pharmaceuticals should not cause you to incur "sleep debt". In addition, there was information about the lack of addiction to modafinil and greater safety compared to classic stimulants. All this made modafinil interested primarily in corporate employees (especially senior management), as well as pre-session students, athletes, military people who conduct long-term operations and others who want to maintain full concentration, improve the ability to focus, increase motivation while performing tasks , significantly increase the effectiveness of learning and improve memory, because such effects are given by modafinil. In addition, modafinil reduces jet lag. It was for this purpose that the President of the United States, Barack Obama, was supposed to use it on his business trips .¹
Several studies have been conducted to evaluate the effects of modafinil. One of them compared the effects of dextroamphetamine (a drug that stimulates the nervous system - at a dose of 20 mg), caffeine (600 mg) and modafinil (400 mg) in healthy volunteers. People deprived of sleep for 64 hours performed simple tasks - the speed of their execution and the number of mistakes made were measured.
1. Characteristics of the substance modafinil
Modafinil is a neurostimulant. In the United States, it is known as Provigil. Its task is to stimulate the brain. Modafinil has been used to treat narcolepsy, ADHD and depression. Despite its effectiveness, Modafinil has not been approved as a drug for ADHD. Modafinil is considered to be the perfect "doping" for the brain.
Modafinil is not narcotic. Even its building does not resemble narcotic stimulants such as amphetamines, cocaine or methylphenidate. However, it cannot be completely excluded that Modafinil will be addictive. Modafinil is effective for 15 hours. It is usually applied in the morning, right after waking up.
Modafinil - what is it?
Modafinil is a drug for narcolepsy, a disease involving excessive daytime sleepiness. It affects the activity of areas of the brain that control the rhythm of sleep and wakefulness. It belongs to the group of eugeroics. Eugeroics are substances that put you on alert and alert. It is also a nootropic drug that is often used off label.
The most famous form is the racemate, a mixture of two enantiomers - R and S-modafinil. The R-enantiomer, also known as armodafinil, is the stronger "brother", therefore in isolated form it is also produced as a drug, and its effectiveness is visible at slightly lower doses than in the case of modafinil.
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